NEUROD2 Antibody
NSJ-V9445SAF-100UG 100 ug
Data Sheet: 
Reactivity
Human
Applications
ELISA, FACS, IF
Source / Host
Mouse
Immunogen
Recombinant full-length human NEUROD2 protein was used as the immunogen for the NEUROD2 antibody.
Clone
PCRP-NEUROD2-1G1
Purity
Protein A/G affinity
Long Term Storage
Aliquot the NEUROD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Description
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
