NAS-181
CAY-39191-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1217474-40-2
Formulation
A solid
Purity
≥95%
MW
538,63414
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A 5-HT1B receptor antagonist (Ki = 47 nM); selective for 5-HT1B over 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = >3,000 nM for all for the rat receptors); potentiates potassium-stimulated 5-HT release in isolated and preloaded rat occipital cortical slices at 100 or 1000 nM; increases extracellular levels of ACh, but not glutamate or GABA, in the frontal cortex and ventral hippocampus of non-anesthetized rats at 1, 5, or 10 mg/kg; induces wet-dog shakes in rats at 3 mg/kg, which can be prevented by p-chloro phenylalanine; increases the length of freezing time induced by contextual fear conditioning in mice
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
