
CAS
81117-35-3
Formulation
A solid
Purity
≥98%
MW
289,41098
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively); increases hepatic glycogen levels in fasted mice and gastrocnemius muscle glycogen levels in both fasted and fed mice at 250 mg/kg per day; increases β-glucosidase activity by 1.65-fold in patient-derived fibroblasts homozygous for the N370S Gaucher disease mutation when added to the culture medium at 5 μM, but inhibits β-glucosidase activity at >60 μM; DNJ inhibits viral replication in BHK-21 cells JEV or DEN-2); has protective effects in a mouse model of lethal JEV challenge at 200 mg/kg per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).