Masitinib
CAY-13105-10 10 mg
Synonyms: AB-1010|Masican|Masiviera
Data Sheet: 
SDS:
SDS:
CAS
790299-79-5
Formulation
A crystalline solid
Purity
≥98%
MW
498,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of c-Kit (IC50 = 200 nM); an inhibitor of PDGFRα, PDGFRβ, and Lyn B (IC50s = 540, 800, and 510 nM, respectively); inhibits stem cell factor-induced proliferation of Ba/F3 cells expressing wild-type KIT (IC50 = 150 nM), as well as those expressing the KIT mutants KITV559D and KITΔ27 (IC50s = 3 and 5 nM, respectively); an inhibitor of SARS-CoV-2 Mpro (Ki = 2.6 µM); inhibits replication of SARS-CoV-2 in infected A549 cells (EC50 = 3.2 µM); decreases lung and nose viral titers, as well as reduces lung inflammation and increases survival, in ACE2-humanized mice infected with SARS-CoV-2 at 25 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
