MUC4 Antibody / Mucin-4
NSJ-V7541-100UG 100 ug
Data Sheet: 
Reactivity
Human
Applications
IHC-P
Source / Host
Mouse
Immunogen
Amino acids 1730-1864 from the human protein were used as the immunogen for this MUC4 antibody.
Clone
MUC4/3084
Purity
Protein G affinity chromatography
Long Term Storage
Store the MUC4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Description
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
