Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

MST-312

  CAY-24301-10 10 mg

 
Synonyms: Telomerase Inhibitor IX
 
Cayman
MST-312

Data Sheet:     SDS:    

CAS
368449-04-1  

Formulation
A crystalline solid  

Purity
≥98%  

MW
380,35092  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
A telomerase inhibitor (IC50 = 0.67 μM in a TRAP assay); selective for telomerase over DNA polymerase (3 μM); inhibits growth of U937 cells (GI50 = 1.7 μM); reduces cell number and expression of the proliferation marker MIB-1 as well as increases DNA damage in primary pediatric ependymoma tumor cells; decreases survival of H460 and H1299 NSCLC cells; reduces tumor size by 70% in an H460 mouse xenograft model (40 mg/kg); inhibits replication of HSV-2 and a clinical isolate of HSV-1; decreases accumulation of early and late viral proteins in HEp-2 cells infected with HSV-1
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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