CAS
264622-58-4
Formulation
A crystalline solid
Purity
≥95%
MW
486,52268
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An adenosine A2B receptor antagonist (Ki = 1.97 nM); selective for adenosine A2B receptors over adenosine A1, A2A, and A3 receptors (Kis = 403, 503, and 570 nM, respectively); increases 28-day survival, as well as decreases peritoneal bacterial growth and plasma levels of IL-6, TNF-α, and MIP-2, in a mouse model of CLP-induced sepsis from 0.5-10 mg/kg; reduces disease severity in a mouse model of EAE at 1 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).