Lu AF21934
CAY-27045-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1445605-23-1
Formulation
A crystalline solid
Purity
≥98%
MW
315,19452
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A positive allosteric modulator of mGluR4 (EC50 = 500 nM for the human receptor in a FLIPR assay); selective for mGluR4 over mGluR6 (EC50 = 7 μM) and a panel of 73 CNS ion channels, GPCRs, and enzymes at 10 μM; reduces marble burying behavior and stress-induced hyperthermia in mice at 12 mg/kg but also reduces locomotor activity; inhibits MK-801- and amphetamine-induced hyperactivity in mice; prevents MK-801-induced decreases in social interaction in rats; reduces harmaline-induced hyperactivity in rats at 0.5 and 2.5 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
