Lirafugratinib
CAY-40940-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
2549174-42-5
Formulation
A solid
Purity
≥98%
MW
509,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A covalent FGFR2 inhibitor (IC50 = 0.003 µM); selective for FGFR2 over FGFR1, -3, and -4 (IC50s = 0.77, 0.26, and 15 µM, respectively); inhibits the proliferation of SNU-16 cells (IC50 = 0.002 µM); reduces intratumoral FGFR2 phosphorylation and tumor volume in an FGFR2-amplified SNU-16 gastric cancer mouse xenograft model at 10 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
