LP-01
CAY-37278-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1799316-64-5
Formulation
A solution in methyl acetate
Purity
≥95%
MW
852,3
Shipment
-20
Long Term Storage
-20
Shelf Life
730
Description
An ionizable cationic lipid (pKa = ~6.1); LNPs containing LP-01 and encapsulating both Cas9 mRNA and modified sgRNA for Ttr induce gene editing in liver cells in mice in a dose-dependent manner resulting in reduced serum Ttr levels for at least 12 months; subretinal administration of LNPs containing LP-01 and encapsulating both Cas9 mRNA and sgRNA targeting the loxP stop codon induce retinal gene editing in Ai9 mice
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
