JQKD82 (hydrochloride)
CAY-41542-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
2863676-87-1
Formulation
A solid
Purity
≥98%
MW
610
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A prodrug form of KDM5-C49; increases the levels of H3K4me3 in MOLP-8 and MM.1S cells at 0.3 and 1 µM; reduces the proliferation of MOLP-8 and MM.1S cells in a concentration-dependent manner; decreases the viability of primary CD138+ cells from patients with multiple myeloma at 3 µM; induces cell cycle arrest at the G0/G1 phase, as well as induces apoptosis, in MOLP-8 and MM.1S cells at 1 µM; decreases tumor growth and increases survival in a MOLP-8 mouse xenograft model at 50 mg/kg twice per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
