JPH203
CAY-29715-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1037592-40-7
Formulation
A crystalline solid
Purity
≥98%
MW
472,32018
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of LAT1 (IC50 = 0.14 μM for 14C-leucine uptake in S2 cells expressing the human transporter); selective for LAT1 over LAT2 (IC50 = >10 μM); inhibits 14C-leucine uptake by, and growth of, HT-29 cells (IC50s = 0.06 and 4.1 μM, respectively); induces apoptosis and increases levels of cleaved caspase-3, caspase-7, caspase-9, and PARP in YD-38 oral cancer cells at 3 mM; reduces tumor growth in an HT-29 mouse xenograft model at 6.3, 12.5, and 25 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
