JNJ-303
CAY-37345-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
878489-28-2
Formulation
A solid
Purity
≥98%
MW
440,98474
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of Kv.1 (IC50 = 0.064 µM); selective for inhibiting IKs over INa, IKr, Ito, IK1, and ICaL (IC50s =3.3, 12.6, 11.1, >100, and >10 µM, respectively); selectively inhibits the heteromeric Kv7.1-KCNE1 complex (IC50 = 0.0784 µM) with no effect on homomeric Kv7.1, Kv7.2, or Kv1.5 in Xenopus oocytes at 1 µM; prolongs the QT interval and also induces pause-dependent TdP in anesthetized dogs at 0.63 and 1.25 mg/kg, respectively
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
