Iclepertin
CAY-41729-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1421936-85-7
Formulation
A solid
Purity
≥98%
MW
512,423819
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A GlyT1 inhibitor (IC50s = 5 and 5.2 nM for the human and rat transporter, respectively); selective for GlyT1 over GlyT2 (IC50 = >10 µM for the human transporter); increases CSF levels of glycine in rats when administered at doses of 0.2, 0.6, or 2 mg/kg; improves learning and memory in the social recognition test in rats at 0.2, 0.6, or 1.8 mg/kg; reverses MK-801-induced working memory deficits in the T-maze test in mice at 0.5, 1.5, or 4.5 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
