Icatibant (acetate)
CAY-24083-500 500 µg
Data Sheet: 
SDS:
SDS:
CAS
138614-30-9
Formulation
A crystalline solid
Purity
≥98%
MW
1304,52422
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A synthetic peptide antagonist of the bradykinin B2 receptor (IC50 = 1.07 nM; Ki = 0.798 nM); inhibits bradykinin-induced contractions in isolated guinea pig ileum and pulmonary arteries as well as in rat uterus (IC50s = 11, 5.4, and 4.9 nM, respectively); inhibits bradykinin-induced bronchoconstriction in a guinea pig model (ID50s = 13.4 and 31.8 pmol/kg, i.v., for pulmonary resistance and dynamic lung compliance, respectively); reduces vascular permeability in a mouse model of hereditary angioedema (30 µg, i.v.)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
