IPA-3
CAY-14759-25 25 mg
Synonyms: Inhibitor of PAK1 Activation 3
Data Sheet: 
SDS:
SDS:
CAS
42521-82-4
Formulation
A crystalline solid
Purity
≥95%
MW
350,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of PAK1 activation (IC50 = 2.5 µM); does not inhibit pre-activated PAK1; selectively inhibits PAK1, PAK2, and PAK3 activation over PAK4, PAK5, and PAK6 activation at 10 µM; inhibits SARS-CoV-2 nsp15 in a FRET assay (IC50 = 6.8 µM); inhibits SARS-CoV-2 replication in infected Vero CCL-81 cells (IC50 = 8.5 µM); inhibits the proliferation of H2M and MHCC97-L cells at 5 and 10 µM; reduces tumor growth in an MHCC97-L cell mouse xenograft model at 2 and 4 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
