CAS
313254-51-2
Formulation
A crystalline solid
Purity
≥98%
MW
449,54738
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A selective Nav1.1 and Nav1.3 channel blocker (IC50s = 10,000 nM for Nav1.1, Nav1.3, Nav1.4, and Nav1.5-1.8, respectively); induces a concentration-dependent hyperpolarizing shift in voltage dependence of inactivation of Nav1.3 channels at 1 μM; substitution of the Nav1.3 VSD4 with the Nav1.5 VSD4 reduces potency by ~500-fold
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).