Human Osteopontin (OPN) ELISA
BLA-BA1028 96 wells
Data Sheet: 
Sample Type
Serum, Plasma
Assay Range
4000 - 125 pg/ml
Description
Osteopontin (OPN), a secreted multifunctional phosphoprotein, is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of cell matrix proteins and participates in many biological activities. OPN has been demonstrated to be closely related to the occurrence and development of many bone-related diseases, such as osteoporosis, rheumatoid arthritis, and osteosarcoma.1 Besides that, it functions as a proinflammatory cytokine and promotes cell-mediated immune responses, and also has protective functions such as biomineralization [20,22,23] and wound healing, and is also a strong predictor of adverse outcomes in patients with CVDs [30–32]. Thus, OPN is not only a risk factor but also a potential therapeutic target for CVDs.2
Enzyme Immunoassay for the quantitative determination of Osteopontin in human serum and plasma.
RESOURCE
Si J, Wang C, Zhang D, Wang B, Zhou Y. Osteopontin in Bone Metabolism and Bone Diseases. Med Sci Monit. 2020 Jan 30;26:e919159. doi: 10.12659/MSM.919159. PMID: 31996665; PMCID: PMC7003659.
Shirakawa K, Sano M. Osteopontin in Cardiovascular Diseases. Biomolecules. 2021 Jul 16;11(7):1047. doi: 10.3390/biom11071047. PMID: 34356671; PMCID: PMC8301767
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
