Hesperidin
CDX-H0245-G100 100 g
Synonyms: Cirantin; Hesperidoside; NSC 44184; Hesperetin 7-rhamnoglucoside; Hesperitin-7-rutinoside; Diosmin EP Impurity B
Data Sheet: 
Source / Host
Isolated from plant source.
CAS
520-26-3
Purity
>98% (HPLC)
MW
610.56
Shipment
Ambient
Short Term Storage
+4°C
Long Term Storage
+4°C
Shelf Life
Stable for at least 2 years after receipt when stored at +4°C.
Description
Chemical. CAS: 520-26-3. Formula: C28H34O15. MW: 610.56. Isolated from plant source. Hesperidin is a flavanone rutinoside first isolated from citrus peels. It is metabolized by intestinal bacteria to an aglycone form, hesperetin, which is thought to be more bioavailable due to reduced polarity that allows for increased cell permeability. Both hesperidin (Hsd) and its aglycone hesperetin (Hst) have various biological properties. Studies have shown both anti-cancer and cancer chemopreventive effects, associated with their antioxidant, radical scavenging and anti-inflammatory activities. In addition, Hsd and Hst interfere at different stages of cancer. They inhibit tumor growth by targeting multiple cellular protein targets at the same time, including caspases, Bcl-2 and Bax for the induction of apoptosis, and COX-2, MMP-2 and MMP-9 for the inhibition of angiogenesis and metastasis. They also have show cardioprotective, neuroprotective and antimicrobial effects.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
