HSP90α (N-Terminal) Geldanamycin Competitive Inhibitor Assay Kit
BPS-50293 96 reactions
Synonyms: HSP90a, Heat Shock Protein 90a, HSP90alpha, HSP90α
Data Sheet: 
Applications
Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Shipment
-80°C (dry ice)
Literature References
1. Kim, J., et al. J Biomol Screening 2004, 9(5): 375-381.
2. Howes, R., et al. Anal Biochem 2006, 350:202-213.
Application Reference(s):
1. The quinone methide aurin is a heat sho
Description
The HSP90α Assay Kit is designed for identification of HSP90α inhibitors using fluorescence polarization. The assay is based on the competition of fluorescently labeled geldanamycin for binding to purified recombinant HSP90α. The key to the HSP90α Assay Kit is the fluorescently labeled geldanamycin. Using this kit, only one simple step on a microtiter plate is required for HSP90α reactions. The fluorescently labeled geldanamycin is incubated with a sample containing HSP90α enzyme to produce a change in fluorescent polarization. The FP signal is measured using a fluorescent microplate reader capable of measuring fluorescence polarization. - Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. - Avoid freeze/thaw cycles.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
