
CAS
1422955-31-4
Formulation
A solid
Purity
≥98%
MW
308,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of HIF-2α PAS-B domain heterodimerization; binds to the HIF-2α PAS-B domain (Kd = 81 nM) to inhibit heterodimerization with the ARNT PAS-B domain in cell-free assays from 0.1-100 µM; decreases expression of the HIF-2α target gene VEGFA in 786-O renal carcinoma cells from 0.1-30 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).