HDAC9 Fluorogenic Assay Kit
BPS-50069 96 reactions
Synonyms: histone deacteylase, HDAC9
Data Sheet: 
Applications
Great for studying enzyme kinetics and screening small molecular inhibitors of HDAC9 for drug discovery and HTS applications.
Shipment
-80°C (dry ice)
Literature References
Ontoria, J.M., et al., J. Med. Chem. 2009 Nov 12;52(21):6782-9.
Description
The Fluorogenic HDAC9 Assay Kit is a complete assay system
designed to measure histone deacetylase 9 (HDAC9) activity for screening and profiling
applications. It comes in a convenient 96-well format, with all the reagents necessary for
100 fluorescent HDAC9 activity measurements. In addition, the kit includes purified
HDAC9 enzyme and a potent HDAC inhibitor, Trichostatin A, for use as a positive and
negative control. The Fluorogenic HDAC9 Assay Kit is based on a unique fluorogenic
substrate and developer combination. This assay method eliminates dealing with the
radioactivity, extraction, and chromatography aspects of traditional assays. Using this kit,
only two simple steps on a microtiter plate are needed to analyze the HDAC9 activity
level. First, the HDAC fluorometric substrate, containing an acetylated lysine side chain,
is incubated with purified HDAC9. The deacetylation sensitizes the substrate so
subsequent treatment with the Lysine Developer produces a fluorophore that can then
be measured using a fluorescence reader.
- Great for studying enzyme kinetics and screening small molecular inhibitors of HDAC9 for drug discovery and HTS applications. - Avoid freeze/thaw cycles.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
