H3B-6527
CAY-26072-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1702259-66-2
Formulation
A solid
Purity
≥98%
MW
629,53718
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An FGFR4 inhibitor (IC50 = 50s = 320, 1,290, and 1,060 nM, respectively), as well as TAOK2, JNK2, and CSF1R (IC50s = 690, >10,000, and >10,000 nM, respectively); decreases cell growth (GI50 = 25 nM) and increases caspase-3/7 activity in Hep3B HCC cells; selectively inhibits cell growth in HCC cell lines that express high levels of FGF19; reduces tumor growth in a Hep3B HCC mouse xenograft model at 100 and 300 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
