GSK2256098
CAY-22955-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1224887-10-8
Formulation
A crystalline solid
Purity
≥98%
MW
414,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A FAK inhibitor; selective for FAK over 261 kinases; inhibits FAK autophosphorylation at Y397 in OVCAR8 ovarian, U87MG glioblastoma, and A549 lung cancer cell lines (IC50s = 15, 8.5, and 12 nM, respectively); induces apoptosis, decreases viability (IC50 = 25 µM), and inhibits colony formation in L3.6P1 cells; leads to lower tumor weight and fewer metastases in an orthotopic mouse model of uterine cancer at 75 mg/kg per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
