Synonyms: Glucagon-like Peptide 1 Receptor Agonist DMB


CAS
281209-71-0
Formulation
A crystalline solid
Purity
≥98%
MW
348,24862
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A GLP-1R agonist (KB = 26.3 nM for the recombinant human receptor); inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor (EC50 = 101 nM); increases glucose-induced insulin levels in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice at 100 and 1,000 nM; reduces fasting plasma glucose levels in mice at 5 µmol/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).