CAS
2304549-73-1
Formulation
A solid
Purity
≥98%
MW
386,759209
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A TRPC5 inhibitor (IC50 = 0.18 µM); selective for TRPC5 over TRPC6 and Nav1.5 (IC50s = >30 µM for both) and a panel of 100 receptors and kinases at 10 µM but does inhibit TRPC4 (IC50 = 0.29 µM); decreases urinary excretion of total protein and albumin in a rat model of high salt- and unilateral nephrectomy-induced renal hypertension at 30 mg/kg per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).