
CAS
347174-05-4
Formulation
A crystalline solid
Purity
≥98%
MW
262,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A ferroptosis inhibitor; inhibits cell death induced by erastin (EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells at 0.5 μM; inhibits erastin-induced production of ROS and lipid peroxidation in HT-1080 cells at 0.5 μM; increases cell survival in cell-based models of Huntington’s disease, periventricular leukomalacia, and kidney proximal tubule damage; inhibits cell death induced by L-glutamate in a rat OHSC model at 2 μM; inhibits autooxidation of lipids by trapping peroxyl radicals`
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).