Ensitrelvir
CAY-37945-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
2647530-73-0
Formulation
A crystalline solid
Purity
≥95%
MW
531,877749
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of SARS-CoV-2 Mpro (IC50 = 0.013 µM); selective for Mpro over HIV-1 protease and the human proteases caspase-2, chymotrypsin, thrombin, and cathepsin B, -D, -G, and -L (IC50s = >100 µM for all); reduces the cytopathic effects of SARS-CoV-2 clinical isolates, including Alpha, Beta, Gamma, Delta, and Omicron strains, SARS-CoV, and MERS-CoV, in Vero E6 cells expressing human TMPRSS2 (EC50s = 0.29-1.4 µM); decreases lung viral titers in a mouse model of SARS-CoV-2 Gamma variant infection when administered at the time of, and 12 hours after, infection from 2-32 mg/kg, p.o.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
