
CAS
7599-79-3
Formulation
A crystalline solid
Purity
≥95%
MW
598,1
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Enclomiphene is an estrogen receptor (ER) modulator.{53931,53932,53933} It acts as an ER antagonist in humans, sheep, and rabbits and an ER agonist in rats.{53931,53932,53933} Enclomiphene (0.34 µM) inhibits binding of 17β-estradiol (E2; Item No. 10006315) in isolated rabbit uterus.{53932} It decreases E2-induced inhibition of follicle stimulating hormone (FSH) secretion in primary sheep pituitary cells in a concentration-dependent manner.{53933} Enclomiphene (0.25 and 0.5 mg/animal) inhibits spermatogenesis and decreases serum luteinizing hormone (LH) and testosterone levels in intact or castrated rats.{53934} Formulations containing enclomiphene have been used in the treatment of ovarian dysfunction.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).