Emetine (hydrochloride hydrate)
CAY-21048-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
7083-71-8
Formulation
A crystalline solid
Purity
≥85%
MW
553,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An alkaloid with diverse biological activities; active against several strains of E. histolytica amoebae (IC50s = 0.73-10.22 μg/ml); inhibits NF-κB signaling induced by TNF-α or IL-1β (IC50s = 2 and 4.2 μM, respectively, in a cell-based β-lactamase reporter assay); increases caspase-3/7 activity in ME180 cells (EC50 = 1.1 μM); cytotoxic to HeLa cells; reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 0.46 and 0.5 μM, respectively); induces emesis in ferrets at 5 mg/kg, an effect that can be prevented by ondansetron
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
