Dooku1
CAY-39161-50 50 mg
Data Sheet: 
CAS
2253744-54-4
Formulation
A solid
Purity
≥98%
MW
326,2
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An antagonist of yoda1-activated Piezo1 (IC50 = 1.3 µM in HEK293 cells expressing the human receptor); selective for yoda1-actived Piezo1 over constituitively active Piezo1, TRPV4, and TRPC4 at 10 µM; reduces the percentage of cells with yoda1-induced extracellular phosphatidylserine exposure in RBCs isolated from patients with sickle cell anemia at 10 µM; inhibits yoda1-induced relaxation of isolated mouse aortic rings at 10 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
