
CAS
1263774-59-9
Formulation
A solid
Purity
≥98%
MW
310,35396
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of JAK1, JAK2, JAK3, and TYK2 (IC50s = 2.8, 2.6, 13, and 58 nM, respectively); is selective for JAK1, JAK2, JAK3, and TYK2 over LCK (IC50 = 5,800 nM); inhibits IL-31-induced increases in STAT3 phosphorylation levels in A549 cells (IC50 = 25 nM); reduces IL-31-induced scratching in mice in a dose-dependent manner
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).