CAS
346692-04-4
Formulation
A crystalline solid
Purity
≥98%
MW
307,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A FFAR1 (GPR40) antagonist that inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic, oleic, palmitoleic, and lauric acid with IC50 values of 6.28, 5.96, 7.07, and 4.58 µM, respectively; inhibits glucose-stimulated insulin secretion, reduces blood insulin levels, improves insulin sensitivity, and decreases the rate of pancreatic β-cell apoptosis in obese diabetic db/db mice at 10 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).