Crotonoside
CAY-28219-10 10 mg
Synonyms: 2-Hydroxyadenosine|Isoguanine riboside|Isoguanosine|NSC 12161
Data Sheet: 
SDS:
SDS:
CAS
1818-71-9
Formulation
A crystalline solid
Purity
≥95%
MW
283,24092
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A guanosine analog with diverse biological activities; cytotoxic to P338, L5178Y, Sp2/O, HL-60, and Raji cells in vitro (EC50s = 21, 370, 120, 70, and 400 μM, respectively); reduces tumor growth by 60% in S-180 sarcoma and Ehrlich carcinoma solid tumor mouse models at 48 mg/kg per day for 12 days; has been used as an internal standard for the semi-quantitative analysis and comparison of RNA metabolites in MCF-7 breast cancer cells and MCF-10A mammary epithelial cells; decreases the force and rate of contraction in isolated guinea pig atria (EC50s = 2.8 and 17.8 μM, respectively); reduces carotid blood pressure in anesthetized cats at 0.5 μmol/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
