
CAS
181144-66-1
Formulation
A solid
Purity
≥95%
MW
273,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A state-dependent sodium channel inhibitor; selectively binds to inactivated Nav channels over resting Nav channels (Kis = 0.6 and >15 µM, respectively); inhibits INa in primary rat acutely dissociated hippocampal neurons at 1 µM; inhibits early- and late-phase nociceptive responses in the formalin test in mice (ED50s = 10.6 and 5.2 mg/kg, respectively); reduces the number of MES-induced tonic seizures in mice and rats
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).