
CAS
145672-81-7
Formulation
A solid
Purity
≥95%
MW
1431,1
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A synthetic peptide GnRHR antagonist (Kd = 0.2 nM); inhibits [D-Trp6]GnRH-induced activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells (IC50 = 1.2 nM); reduces tumor volume and serum luteinizing hormone levels by 35% and 50% of control, respectively, in a human epithelial ovarian cancer mouse xenograft model at 60 μg per day; increases PMF survival in ovaries in cyclophosphamide treated mice at 0.5 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).