CAS
1026249-18-2
Formulation
A solid
Purity
≥98%
MW
242,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dual agonist of TLR7 and TLR8; induces activation of NF-κB in HEK293 cells expressing human TLR7 or TLR8 at 0.1 and 1 µg/ml, respectively; induces TNF-α production and enhances LPS- or hyaluronic acid-induced TNF-α, IL-10, and IL-12 production in isolated human monocyte-derived macrophages; increases pancreatic lymph node IFN-α levels in pre-diabetic NOD mice
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).