CAS
301356-95-6
Formulation
A solid
Purity
≥98%
MW
457,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A Bcl-6 inhibitor (Ki = 147 µM); selective for Bcl-6 over Kaiso, HIC1, and PLZF at 50 µM; cytotoxic against SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 DLBCL cells (GI50s = 0.024-0.936 mM); increases expression of ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells at 50 µM; reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models at 50 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).