CAS
346640-08-2
Formulation
A crystalline solid
Purity
≥98% (mixture of isomers)
MW
378,44898
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A PDI inhibitor; inhibits the reducing capacity of PDI at 1 µM; inhibits proliferation in ten multiple myeloma cell lines (IC50s = 50 = <1 µM) but not to NLBM cells up to 6.75 µM; induces acute ER stress and increases the amount of misfolded ER proteins; increases survival in a 5TGM1 mouse syngeneic model of myeloma at 10 mg/kg three times per week
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).