CC-671
CAY-26184-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1618658-88-0
Formulation
A crystalline solid
Purity
≥95%
MW
512,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dual inhibitor of Mps1/TTK and Clk2 (IC50s = 5 and 3 nM, respectively); selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 μM; inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM, respectively); selectively inhibits the growth of Cal-51 TNBC cell over BT-474 luminal breast cancer cells (IC50s = 60 and 6,970 nM, respectively); reduces tumor volume in a Cal-51 mouse xenograft model at 20 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
