
CAS
363600-92-4
Formulation
A crystalline solid
Purity
≥95%
MW
285,29464
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of TLR2 signaling; inhibits synthetic and bacterial TLR2 agonist-induced TLR2/1 and TLR2/6 signaling in HEK-TLR2 cells at 50 µM; decreases the PAM3CSK4-induced expression of IL-8 in HEK-TLR2 cells; inhibits the Pam3CSK4-induced TLR2-MyD88 interaction, blocks MAPK activation, and decreases NF-κB activation and IκBα degradation in THP-1 cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).