Bindarit
CAY-11479-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
130641-38-2
Formulation
A crystalline solid
Purity
≥98%
MW
324,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of MCP production; selective for MCP-1/CCL2, MPC-3/CCL7, and MCP-2/CCL8; inhibits LPS- or C. albicans-induced production of MCP-1/CCL2 in isolated human monocytes (IC50s = 172 and 403 µM, respectively); delays the onset of proteinuria and prolongs survival in a mouse model of experimental lupus nephritis at 50 mg/kg; prevents LPS-induced increases in MCP-1/CCL2 expression in mouse brain and spinal cord when administered at a dose of 200 mg/kg; a noncompetitive inhibitor of MCT4 (Ki = 30.2 µM) that is selective for MCT4 over MCT1
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
