Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

Bestatin (hydrochloride)

  CAY-70520-25 25 mg



CAS
65391-42-6  

Formulation
A crystalline solid  

Purity
≥98%  

MW
344,8  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
An aminopeptidase inhibitor; inhibits aminopeptidase B (IC50 = 0.05 µg/ml), aminopeptidase N (IC50 = 16.9 µM), leucine aminopeptidase (IC50 = 0.01 µg/ml), and the aminopeptidase activity of LTA4 hydrolase (Kapp = 172 nM); selective for these aminopeptidases over aminopeptidase A, trypsin, chymotrypsin, elastase, papain, pepsin, and thermolysin; inhibits LTB4 production in erythrocytes at 70 µM; increases the expression of Akt, inhibits proliferation, migration, and invasion, and induces autophagy and apoptosis in 5637 bladder cancer cells; decreases serum levels of LTB4 and reduces tumor growth in a PDX mouse model of colorectal cancer at 5 and 15 mg/kg
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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