
CAS
136553-81-6
Formulation
A crystalline solid
Purity
≥95%
MW
610,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A peptide ETA receptor antagonist (IC50 = 7.3 nM); selective for ETA over ETB receptors (Kis = 0.025 and 31 µM, respectively); inhibits ET-1-induced growth of human pulmonary artery smooth muscle cells; reverses ET-1-induced increases in MAP in rats; delays seizure onset and reduces the number of rats with major seizures in a model of PTZ-induced epilepsy at 3 mg/kg, i.v.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).