BP-897
CAY-25831-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
314776-92-6
Formulation
A crystalline solid
Purity
≥98%
MW
454,004
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dopamine D3 receptor partial agonist; selectively binds to the dopamine D3 over the D2, D1, and D4 receptors (Kis = 0.92, 61, 3,000, and 300 nM, respectively, for the recombinant human receptors); selective over α1- and α2-adrenergic receptors (Kis = 60 and 83 nM, respectively) and the serotonin receptor subtypes 5-HT1A and 5-HT7 (Kis = 84 and 345 nM, respectively), as well as muscarinic, histamine, and opioid receptors (Kis = >1 µM for all); increases mitogenesis in NG 108-15 cells with a maximum efficacy of 55%; acts as a dopamine D3 receptor antagonist in a [35S]GTPγS binding assay, inhibiting the effect of dopamine (IC50 = 416.87 nM); reduces cocaine-seeking behavior, but has no reinforcing properties itself, in rats trained to self-administer cocaine at 0.5 and 1 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
