CAS
468740-43-4
Formulation
A crystalline solid
Purity
≥98%
MW
480
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dual inhibitor of IGF-1R kinase and IR (IC50s = 100 and 73 nM, respectively); blocks IFG-1R autophosphorylation and signaling through MEK1/2 and Akt, leading to G1 arrest and apoptosis in ML-1 cells; reverses EMT in MCF10A cells overexpressing constitutively activated IGF-1R
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).