CAS
334951-90-5
Formulation
A solid
Purity
≥98%
MW
494,62742
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An ALK5 inhibitor (IC50 = 34 nM); selective for ALK5 over VEGFR2 and PDGFRα (IC50s = 1,447 and 890 µM, respectively), as well as a panel of 30 other kinases at 1 µM; inhibits the phosphorylation of SMAD2 and SMAD3 in HaCaT cells (EC50 = 105 nM); not cytotoxic to HaCaT cells (IC50 = >1,000 nM)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).