BI-9627
CAY-27640-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1204329-34-9
Formulation
A solid
Purity
≥95% (mixture of tautomers)
MW
356,343029
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An NHE1 inhibitor (IC50s = 6 and 31 nM in pHi and human platelet swelling assays, respectively); greater than 30-fold selective for NHE1 over NHE2 and is inactive at NHE3 up to 16 μM in a pHi assay; inhibits phenylephrine-induced hypertrophy in neonatal rat cardiomyocytes; increases recovery of left ventricular developed pressure and inhibits increases in LVEDP in a Langendorff isolated perfused rat heart model of ischemia-reperfusion injury at 100 nM; attenuates decreases in left ventricular end-systolic pressure and increases in LVEDP in coronary artery-ligated rats at 45 and 150 ppm in the diet
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
