BGJ398 (phosphate)
CAY-39292-5 5 mg
Synonyms: Infigratinib (phosphate)|NVP-BGJ398 (phosphate)
Data Sheet: 
SDS:
SDS:
CAS
1310746-10-1
Formulation
A solid
Purity
≥98%
MW
658,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A pan FGFR inhibitor (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively); suppresses proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s = 5, 30, 32, and 15 nM, for RT112, RT4, SW780, and JMSU1 cells, respectively); inhibited tumor growth in an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3 at 10-30 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
