Anti-SQSTM1 Antibody
ABI-SQSTM1-0100 500 µL
Synonyms: Sequestosome-1, ORCA, OSIL, P62, Autophagy Receptor P62
Data Sheet: 
Reactivity
Human, Mouse, and Rat
Applications
ICC, IHC, WB
Concentration
200 µg/mL
Shipment
Ice packs
Long Term Storage
Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Shelf Life
12 months from receipt of product
Description
Our Anti-SQSTM1 chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human, mouse, and rat SQSTM1, and is affinity-purified IgY. It is great for use in ICC, IHC, WB. - Sequestosome 1 (SQSTM1), also known as p62, is a multifunctional adaptor protein involved in autophagy, cell signaling, and protein degradation. It plays a key role in selectively targeting ubiquitinated proteins for degradation via the autophagy-lysosome pathway and is also involved in NF-κB signaling, oxidative stress responses, and bone metabolism. Mutations in SQSTM1 are strongly associated with Paget’s disease of bone and have been implicated in neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and certain cancers. Due to its role in cellular homeostasis, SQSTM1 remains a significant focus in research on autophagy-related diseases and targeted therapies. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
